DREAM is a Dialogue for Reverse Engineering Assessments and Methods. The main objective is to catalyze the interaction between experiment and theory in the area of cellular network inference and quantitative model building in systems biology.
Call Np the number of parameters to predict. Each model has a different number of parameters. Models 1, 2 and 3 have N= 34, 41 and 57 parameters to predict. Let’s denote as vipred and vireal the predicted and actual parameters used in the simulations where i runs between 1 and Np.
Pearson: The Pearson correlation between the ideal confidence values (that is, 1 for the twenty AML patients and 0 for other subjects) and the confidence of the predictions for each patient. This measure determined an order amongst the top performing teams whose precision and recall were 1.
Prec: The Precision of the predictions, defined as the fraction of correct AML patients amongst the first 20 predictions.
Cp: The Pearson correlation between the measured promoter activity and the predicted promoter activity. This is a measure of the co-linearity between measured and predicted promoter activities.
Reconstruct the alternatively spliced mRNA transcripts from short-read mRNA-seq data
Important Note
You cannot publish the Gold Standard for Alternative Splicing Challenge without the explicit permission by Gustavo Stolovitzky (gustavo AT us.ibm.com) and Myke Snyder (michael.snyder AT yale.edu)
